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KMID : 0378019750180091176
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New Medical Journal
1975 Volume.18 No. 9 p.1176 ~ p.1180
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Effect of Nalidixic Acid on the Growth of Enteric Bacteriophages
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Moon Young-Suk
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Abstract
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By one step growth and single burst experiments, the effect of nalidixic acid on the growth of six different enteric bacteriophages has been observed. Six phages tested are all strongly inhibited.
In the presence of Nalidixic acid, phage adsorption is unaffected and found to be normal. The small burst of phage-infected cells are not due to poor adsorption of phage particles. Lysozyme (20y/ml in EDTA) treatment of free phage particles at 37 during 50 min does not kill free phage particles.
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